منابع مشابه
Repetitive elements in genomes of parasitic protozoa.
Repetitive DNA elements have been a part of the genomic fauna of eukaryotes perhaps since their very beginnings. Millions of years of coevolution have given repeats central roles in chromosome maintenance and genetic modulation. Here we review the genomes of parasitic protozoa in the context of the current understanding of repetitive elements. Particular reference is made to repeats in five med...
متن کاملTelomerase in kinetoplastid parasitic protozoa.
We have identified telomerase activity in extracts of three evolutionarily diverse kinetoplastid species: Trypanosoma brucei, Leishmania major, and Leishmania tarentolae. Telomerase activity was initially detected in extracts from insect form cells of all three kinetoplastid species by using a modification of the one-tube telomere repeat amplification protocol [Kim, N., et al. (1994) Science 26...
متن کاملTargeting polyamines of parasitic protozoa in chemotherapy.
All parasitic protozoa contain polyamines and in recent years they, and their associated enzymes, have attracted attention as drug targets because they might reveal novel antiparasite therapies. How justified is this approach to drug discovery? In this review, Sylke Müller, Graham Coombs and Rolf Walter summarize the current status of research into drugs that exploit polyamine metabolism of try...
متن کاملFrontiers in research on parasitic protozoa.
Frontiers in research on parasitic protozoa was the theme of the Autumn Symposium of the British Section of the Society of Protozoologists, held 2 September 2002, in London, UK.
متن کاملProtein arginine methylation in parasitic protozoa.
Protozoa constitute the earliest branch of the eukaryotic lineage, and several groups of protozoans are serious parasites of humans and other animals. Better understanding of biochemical pathways that are either in common with or divergent from those of higher eukaryotes is integral in the defense against these parasites. In yeast and humans, the posttranslational methylation of arginine residu...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2010
ISSN: 1741-7007
DOI: 10.1186/1741-7007-8-64